Excelsior is a gathering spot for the most benevolent and depraved minds. Many of the Alliance will tell Diana that mysterious disappearances are par for the course there - however, they have noticed a sharp uptick in them. All of them seem to be metahumans with obvious inhuman traits, metas who would be desperate for some sort of normalcy without being completely deprived of their powers.

A few mention that a few years back, there was a drug bust in Central City that was doing something similar. The D'Amico family had had its hands in kidnapping and experimentation, all to create drugs that could put baseline soldiers on par with the strongest Metas.

They suggest that she check out one of their old bases around Central. They have locations, and the D'Amico family is most likely still watching them even in their reduced state. It may even be a good idea to try to arrange a meeting with representatives of the family themselves.

It may not be directly related, but coincidences are rare in this business.